Banked blood components

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Whole blood is rarely used (even for blood loss; usually separte components are transfused: red blood cells, platelets, coagulation factors, albumin, leukocyte depleetd cellular componenets. One unit of whole blood - 450 ml blood and 63 ml preservative- with a hematocrit ranging from 36-40%. Packed red cells – 200 mL of cells after removing 200-250 ml plasma- with a hematocrit of 70-80% and stored with citrate-phosphate- dextrose- adenine(CPD- A)

  1. citrate binds ionized Ca and acts as an anticoagulant
  2. phosphate retards breakdown of 2,3 DPG
  3. dextrose is fuel source for red cells
  1. Risk of transfusion with banked blood products consist of viral infection, immunization, and effects of the substances used for preparation and storage; the autologous transfusions are associated only with the risk related to preparation and storage. Banked blood products have decreased levels of nitric oxid, resulting in post-transfusion increased frequency of myocardial infarction, heart failure, stroke, and death.
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