Edema

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  1. vasogenic
    1. most common seen in tumors, abscesses, hematomas and contusions (occurs later in head injury – not within the first several hours); caused by a breakdown of tight junctions which can be reversed by steroids
  2. cytotoxic
    1. due to anoxia/ischemia and caused by disruption of Na/K ATPase pump; seen following craniocerebral missile wounds; associated with a buildup of intracellular K causing the edema
  3. interstitial
    1. due to fluid from ventricles pushing out into the brain as in hydrocephalus
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