Ehlers-Danlos syndrome (EDS)

From WikiCNS
Jump to: navigation, search
Checkmark.gif This article has been reviewed by the NeuroWiki Editorial Board


(11 different types)

  1. Characterized by hypereleasticity of the skin and hypermobile joints; underlying defect is in collagen synthesis
  2. Skin: changes vary from thin and velvety skin to skin that is either dramatically hyperextensible or easily torn or scarred
  3. Mitral valve prolapse and hernias occur particulary in type I, eye rupture with minimal trauma, kyphoscoliosis can cause respiratory impairment, sclera may be blue in type VI; associated with CC fistulas and arterial narrowing
  4. Type IV (arterial form) are prone to spontaneous rupture of the aorta, cervical vessels disection, puture of the intestines, and other tissues that are rich in type III collagen
  5. Surgery can be more difficult in these patients because of the friability of the tissue;
Personal tools