PINEAL PARENCHYMAL TUMOR OF INTERMEDIATE DIFFERENTIATION
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The diagnostic category of pineal parenchymal tumor of intermediate differentiation has been established to identify lesions that are typified by features placing their degree of malignancy somewhere between those of pineoblastoma and pineocytoma.
These tumors are show histopathologic features of maliganancy, e.g. moderate cellularity, mild muclear atypia, occasional mitoses, and the absence of pineocytomatous rosettes, but do not meet the degree of malignant differentiation consistent with a pineoblastoma.
Pineal parenchymal tumors of intermediate differentiation account for about 10% of all pineal parenchymal tumors, and occur with as peak incidence in adulthood. Pineal parenchymal tumor of intermediate differentiation corresponds to WHO Grade III glioma.