X-ray osteolytic spine

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  1. Most metastases are osteolytic although breast and prostate cancer can cause osteoblastic or sclerotic lesions
  2. Pedicle destruction is the most common plain film finding
  3. A subtle plain film clue to metastatic disease is an indistinct posterior vertebral body margin
  4. Other osteolytic lesions: esoinophilic granuloma, plasmacytoma, hemangioma, brown tumor of hyperparathyroidism, osteomyelitis
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